Fakeeh College for Medical Sciences (FCMS) participated in polio vaccine campaign with Ministry of Health (MOH). A group of nurse-interns with a supervision by teaching staff from FCMS have taken the responsibilities in the Polio Vaccine Campaign activity This activity was conducted with a cooperation with Elazizia Center in Jeddah on the second semester of the academic year 2016-2017. The main aim of this campaign was to increase the public awareness of the Poliomyelitis infection and its devastating impact on people’s lives and well-being. Its among the important steps to prevent such infection in the Kingdom of Saudi Arabia.